菜单总览
— 教职人员 —

叶德全

职位:

校长讲座教授、院长

教育背景:

博士(华盛顿大学)

 

研究领域
药理学,免疫学
Email

richardye@cuhk.edu.cn

个人简介:


叶德全教授1982年本科毕业于上海第二医学院,并于1988年获美国圣路易斯华盛顿大学博士学位。自1989年起先后在Scripps研究所及伊利诺伊大学医学院担任助理教授、副教授、教授,其科研项目获美国国立健康研究院连续资助25年。主要研究方向包括G蛋白偶联受体的信号转导及在固有免疫细胞中的作用,炎症机制和病理模型及相关药物靶标的发现。先后与强生、诺华、GSK等公司开展研发合作,作为第一发明人获批美国专利2项、中国专利1项,共同发明人专利2项。发表SCI学术论文198篇,被引1万多次。于2010年回国担任上海交通大学讲席教授、药学院院长;2015年1月至2019年1月任澳门大学讲座教授。学术兼职包括FASEB Journal副主编,Pharmacological Reviews 副主编,Physiological Reviews副主编, Molecular PharmacologyBritish Journal of Pharmacology 编委。


学术著作:


1,  Cheng N, Liang Y, Du X, Ye, RD. Serum amyloid A promotes LPS clearance andsuppresses LPS-induced inflammation and tissue injury. EMBO Reports 2018 Oct;19(10). pii: e45517;  doi: 10.15252/embr.201745517. PMID: 30126923

2,  Zhang G, Liu J, Wu L, Fan Y, Sun L, Qian F, Chen D, Ye RD. Elevated expression of serum amyloid A 3 protects colon epithelium against acute injury through TLR2-dependent induction of neutrophil IL-22 expression in a mouse model of colitis. Front. Immunol. 2018 Jun 29; 9:1503. doi: 10.3389/fimmu.2018.01503. PMID: 30008720 

3,  Zheng C, Chen D, Zhang Y, Bai Y, Huang S, Zheng D, Liang W, She S, Peng X, Wang P, Mo X, Song Q, Lv P, Huang J, Ye RD, Wang Y. FAM19A1 is a new ligand for GPR1 that modulates neural stem-cell proliferation and differentiation. FASEB J. 2018 May 25:fj201800020RRR. PMID: 29799787

4,  Zhou H, Chen M, Zhang G, Ye RD. Suppression of Lipopolysaccharide-Induced Inflammatory Response by Fragments from Serum Amyloid A. J Immunol. 2017 Aug 1;199(3):1105-1112,doi: 10.4049/jimmunol.1700470.

5,  Zhu Z, Wang L, Hao R, Zhao B, Sun L, Ye RD. Cutting Edge: A Cullin-5-TRAF6 interaction promotes TRAF6 polyubiquitination and lipopolysaccharide signaling. J Immunol. 2016 Jul 1;197(1):21-6. PMID: 27233966.

6,  Ye, R.D., Sun, L. (2015) Emerging functions of serum amyloid A in inflammation. J Leukoc. Biol. 98:923-929. PMID: 26130702.

7,  Ye, R.D. (2014) STIM1 for stimulation of phagocyte NADPH oxidase. Blood 123:2129-30. doi: 10.1182. PMCID: PMC3975253.

8,  Naikawadi, R.P., Cheng, N., Vogel, S. M., Qian, F., Wu, D., Malik, A. B., & Ye, R. D. (2012). A Critical Role for Phosphatidylinositol (3, 4, 5)-Trisphosphate–Dependent Rac Exchanger 1 in Endothelial Junction Disruption and Vascular Hyperpermeability.  Circ. Res. 111, 1517-1527.

9,  Liu, X., Ma, B., Malik, A.B., Tang, H., Yang, T., Sun, B., Wang, G., Minshall, R.D., Li, Y., Zhao, Y., Ye, R.D. and Xu, J. (2012) Bidirectional Regulation of Neutrophil Migration by MAP Kinases. Nat. Immunol. 13:257-264. (R.D. Ye and J. Xu, co-corresponding authors).

10,Ye, R.D., Boulay, F., Wang, J.M., Dahlgren, C., Gerard, C., Parmentier, M., Serhan, C.N., and Murphy, P.M. (2009) International Union of Pharmacology: Nomenclature for the formyl peptide receptor (FPR) family.  Pharmacol. Rev. 61:119-161.